The risk of development of Alzheimer’s disease increases with age. A recent study performed on the factors that affect the production of amyloid β peptide reveals the fact that level of Vitamin D in the body might have something to do with the removal of amyloid β from the brain. Researchers from Tohoku University, Japan stated after an intensive study performed on the aforementioned fact that Vitamin D regulates the expression of proteins and therefore makes it easy for amyloid β peptide to penetrate the blood brain barrier (BBB). The passage of amyloid β across the blood brain barrier (BBB) is affected by some other factors too like the transporter – LRP-1 and P-gp. After crossing this barrier, amyloid β peptide makes its way into the cerebrospinal fluid of the brain and leads to the occurrence of the debilitating neurodegenerative disorder – Alzheimer’s disease
None of us would have ever imagined that gum bacteria drew out from the periodontal region can be of any aid in patterning a flawless treatment plan for curing Alzheimer’s disease. These gum bacteria cause the brain cells to undergo autophagy or self-eating mechanism under which the cells plan their survival and defence against invading organisms by degrading and recycling material into amino acids. These amino acids released by the cells help in the build up of polypeptides within the neurons of nervous system.